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Clinical utility of tumour mutational burden on efficacy of immune checkpoint inhibitors in malignant solid tumours: protocol for a systematic review and meta-analysis

INTRODUCTION: A major development in solid malignancy treatment is the application of immune checkpoint inhibitors (ICIs), which have produced durable responses and increased survival rates. However, the therapeutic effect of ICIs has great heterogeneity in patients with cancer. We propose a systema...

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Detalles Bibliográficos
Autores principales: Xiang, Xuemei, Li, Yunming, Yang, Xiaoguang, Guo, Wang, Zhou, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358952/
https://www.ncbi.nlm.nih.gov/pubmed/35926995
http://dx.doi.org/10.1136/bmjopen-2021-058692