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Pleiotropic Effects of Ticagrelor: Influence on CYP4F2 Gene and Protein Expression in HUVEC and HepG2, and Escherichia coli Bacterial Survival

BACKGROUND: Antiplatelet drugs, such as ticagrelor, which target platelet P2Y(12) receptors, are used for prevention of ischemic heart disease. Ticagrelor is also known to have pleiotropic effects of unknown mechanisms. Ticagrelor could influence the expression of molecules involved in resolution of...

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Detalles Bibliográficos
Autores principales: Meskauskaite, Ugne, Andruskeviciute, Silvija, Ciapiene, Ieva, Giedraitiene, Agne, Lesauskaite, Vaiva, Tatarunas, Vacis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359174/
https://www.ncbi.nlm.nih.gov/pubmed/35959420
http://dx.doi.org/10.2147/DDDT.S357985