Investigation of the “Nose-to-Brain” Pathways in Intranasal HupA Nanoemulsions and Evaluation of Their in vivo Pharmacokinetics and Brain-Targeting Ability

PURPOSE: While developing huperzine A (HupA) to explore new approaches to treating Alzheimer’s disease (AD), intranasal administration was proposed as an alternative route to deliver drugs into the brain. This study aimed to prepare nanoemulsions (NEs) of HupA to investigate their potential “nose-to...

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Detalles Bibliográficos
Autores principales: Jiang, Yueyao, Jiang, Yichuan, Ding, Zhiying, Yu, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359405/
https://www.ncbi.nlm.nih.gov/pubmed/35959279
http://dx.doi.org/10.2147/IJN.S369978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359405/
https://www.ncbi.nlm.nih.gov/pubmed/35959279
http://dx.doi.org/10.2147/IJN.S369978

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