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It Takes Two to Tango: IGF-I and TSH Receptors in Thyroid Eye Disease

CONTEXT: Thyroid eye disease (TED) is a complex autoimmune disease process. Orbital fibroblasts represent the central orbital immune target. Involvement of the TSH receptor (TSHR) in TED is not fully understood. IGF-I receptor (IGF-IR) is overexpressed in several cell types in TED, including fibrocy...

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Detalles Bibliográficos
Autores principales: Girnita, Leonard, Smith, Terry J, Janssen, Joseph A M J L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359450/
https://www.ncbi.nlm.nih.gov/pubmed/35167695
http://dx.doi.org/10.1210/clinem/dgac045