Cargando…

DNA binding by the Rad9A subunit of the Rad9-Rad1-Hus1 complex

The Rad9-Rad1-Hus1 checkpoint clamp activates the DNA damage response and promotes DNA repair. DNA loading on the central channel of the Rad9-Rad1-Hus1 complex is required to execute its biological functions. Because Rad9A has the highest DNA affinity among the three subunits, we determined the doma...

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, Bor-Jang, Gonzales, Rex, Corzine, Sage, Stenson, Emilee, Pidugu, Lakshmi, Lu, A-Lien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359528/
https://www.ncbi.nlm.nih.gov/pubmed/35939452
http://dx.doi.org/10.1371/journal.pone.0272645