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DNA binding by the Rad9A subunit of the Rad9-Rad1-Hus1 complex
The Rad9-Rad1-Hus1 checkpoint clamp activates the DNA damage response and promotes DNA repair. DNA loading on the central channel of the Rad9-Rad1-Hus1 complex is required to execute its biological functions. Because Rad9A has the highest DNA affinity among the three subunits, we determined the doma...
Autores principales: | Hwang, Bor-Jang, Gonzales, Rex, Corzine, Sage, Stenson, Emilee, Pidugu, Lakshmi, Lu, A-Lien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359528/ https://www.ncbi.nlm.nih.gov/pubmed/35939452 http://dx.doi.org/10.1371/journal.pone.0272645 |
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