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Helix 8 in chemotactic receptors of the complement system

Host response to infection involves the activation of the complement system leading to the production of anaphylatoxins C3a and C5a. Complement factor C5a exerts its effect through the activation of C5aR1, chemotactic receptor 1, and triggers the G protein-coupled signaling cascade. Orthosteric and...

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Detalles Bibliográficos
Autores principales: Wisniewski, Szymon, Dragan, Paulina, Makal, Anna, Latek, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359563/
https://www.ncbi.nlm.nih.gov/pubmed/35862436
http://dx.doi.org/10.1371/journal.pcbi.1009994