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Nuclear Prospero allows one-division potential to neural precursors and post-mitotic status to neurons via opposite regulation of Cyclin E

In Drosophila embryonic CNS, the multipotential stem cells called neuroblasts (NBs) divide by self-renewing asymmetric division and generate bipotential precursors called ganglion mother cells (GMCs). GMCs divide only once to generate two distinct post-mitotic neurons. The genes and the pathways tha...

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Detalles Bibliográficos
Autores principales: Mar, Jordan, Makhijani, Kalpana, Flaherty, Denise, Bhat, Krishna Moorthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359583/
https://www.ncbi.nlm.nih.gov/pubmed/35939521
http://dx.doi.org/10.1371/journal.pgen.1010339