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Molecular mechanism of hyperactive tooth root formation in oculo-facio-cardio-dental syndrome

Mutations in the B-cell lymphoma 6 (BCL6) interacting corepressor (BCOR) cause oculo-facio-cardio-dental (OFCD) syndrome, a rare X-linked dominant condition that includes dental radiculomegaly among other characteristics. BCOR regulates downstream genes via BCL6 as a transcriptional corepressor. How...

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Detalles Bibliográficos
Autores principales: Min Soe, Kyaw, Ogawa, Takuya, Moriyama, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359619/
https://www.ncbi.nlm.nih.gov/pubmed/35957990
http://dx.doi.org/10.3389/fphys.2022.946282