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Vitamin D Receptor Genetic Polymorphisms Associate With a Decreased Susceptibility to Extremity Osteomyelitis Partly by Inhibiting Macrophage Apoptosis Through Inhibition of Excessive ROS Production via VDR-Bmi1 Signaling

Background: Previous studies had reported that vitamin D receptor (VDR) gene polymorphisms were related to the development of several inflammatory disorders. However, potential links between such variations and the risk of developing a bone infection and underlying mechanisms remain unclear. This st...

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Detalles Bibliográficos
Autores principales: Zhao, Xing-Qi, Wan, Hao-Yang, He, Si-Ying, Qin, Han-Jun, Yu, Bin, Jiang, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359620/
https://www.ncbi.nlm.nih.gov/pubmed/35957979
http://dx.doi.org/10.3389/fphys.2022.808272