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Prognostic and therapeutic significance of COP9 signalosome subunit CSN5 in prostate cancer

Chromosome 8q gain is associated with poor clinical outcomes in prostate cancer, but the underlying biological mechanisms remain to be clarified. CSN5, a putative androgen receptor (AR) partner that is located on chromosome 8q, is the key subunit of the COP9 signalosome, which deactivates ubiquitin...

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Detalles Bibliográficos
Autores principales: Mazzu, Ying Z., Liao, Yu-Rou, Nandakumar, Subhiksha, Jehane, Lina E., Koche, Richard P., Rajanala, Sai Harisha, Li, Ruifang, Zhao, HuiYong, Gerke, Travis A., Chakraborty, Goutam, Lee, Gwo-Shu Mary, Nanjangud, Gouri J., Gopalan, Anuradha, Chen, Yu, Kantoff, Philip W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359627/
https://www.ncbi.nlm.nih.gov/pubmed/34802033
http://dx.doi.org/10.1038/s41388-021-02118-4