Multistep loading of a DNA sliding clamp onto DNA by replication factor C

The DNA sliding clamp proliferating cell nuclear antigen (PCNA) is an essential co-factor for many eukaryotic DNA metabolic enzymes. PCNA is loaded around DNA by the ATP-dependent clamp loader replication factor C (RFC), which acts at single-stranded (ss)/double-stranded DNA (dsDNA) junctions harbor...

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Detalles Bibliográficos
Autores principales: Schrecker, Marina, Castaneda, Juan C, Devbhandari, Sujan, Kumar, Charanya, Remus, Dirk, Hite, Richard K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359705/
https://www.ncbi.nlm.nih.gov/pubmed/35939393
http://dx.doi.org/10.7554/eLife.78253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359705/
https://www.ncbi.nlm.nih.gov/pubmed/35939393
http://dx.doi.org/10.7554/eLife.78253

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