Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma

Capicua-double homeobox 4 (CIC-DUX4)–rearranged sarcomas (CDS) are extremely rare, highly aggressive primary sarcomas that represent a major therapeutic challenge. Patients are treated according to Ewing sarcoma protocols, but CDS-specific therapies are strongly needed. In this study, RNA sequencing...

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Detalles Bibliográficos
Autores principales: Carrabotta, Marianna, Laginestra, Maria Antonella, Durante, Giorgio, Mancarella, Caterina, Landuzzi, Lorena, Parra, Alessandro, Ruzzi, Francesca, Toracchio, Lisa, De Feo, Alessandra, Giusti, Veronica, Pasello, Michela, Righi, Alberto, Lollini, Pier-Luigi, Palmerini, Emanuela, Donati, Davide Maria, Manara, Maria Cristina, Scotlandi, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Translational Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359717/
https://www.ncbi.nlm.nih.gov/pubmed/34903601
http://dx.doi.org/10.1158/0008-5472.CAN-21-1222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359717/
https://www.ncbi.nlm.nih.gov/pubmed/34903601
http://dx.doi.org/10.1158/0008-5472.CAN-21-1222

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