Chaperone-Mediated Autophagy Controls Proteomic and Transcriptomic Pathways to Maintain Glioma Stem Cell Activity

Chaperone-mediated autophagy (CMA) is a homeostatic process essential for the lysosomal degradation of a selected subset of the proteome. CMA activity directly depends on the levels of LAMP2A, a critical receptor for CMA substrate proteins at the lysosomal membrane. In glioblastoma (GBM), the most c...

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Detalles Bibliográficos
Autores principales: Auzmendi-Iriarte, Jaione, Otaegi-Ugartemendia, Maddalen, Carrasco-Garcia, Estefania, Azkargorta, Mikel, Diaz, Antonio, Saenz-Antoñanzas, Ander, Andermatten, Joaquin Andrés, Garcia-Puga, Mikel, Garcia, Idoia, Elua-Pinin, Alejandro, Ruiz, Irune, Sampron, Nicolas, Elortza, Felix, Cuervo, Ana Maria, Matheu, Ander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Molecular Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359743/
https://www.ncbi.nlm.nih.gov/pubmed/35131870
http://dx.doi.org/10.1158/0008-5472.CAN-21-2161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359743/
https://www.ncbi.nlm.nih.gov/pubmed/35131870
http://dx.doi.org/10.1158/0008-5472.CAN-21-2161

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