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Chaperone-Mediated Autophagy Controls Proteomic and Transcriptomic Pathways to Maintain Glioma Stem Cell Activity

Chaperone-mediated autophagy (CMA) is a homeostatic process essential for the lysosomal degradation of a selected subset of the proteome. CMA activity directly depends on the levels of LAMP2A, a critical receptor for CMA substrate proteins at the lysosomal membrane. In glioblastoma (GBM), the most c...

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Detalles Bibliográficos
Autores principales:	Auzmendi-Iriarte, Jaione, Otaegi-Ugartemendia, Maddalen, Carrasco-Garcia, Estefania, Azkargorta, Mikel, Diaz, Antonio, Saenz-Antoñanzas, Ander, Andermatten, Joaquin Andrés, Garcia-Puga, Mikel, Garcia, Idoia, Elua-Pinin, Alejandro, Ruiz, Irune, Sampron, Nicolas, Elortza, Felix, Cuervo, Ana Maria, Matheu, Ander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Molecular Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359743/ https://www.ncbi.nlm.nih.gov/pubmed/35131870 http://dx.doi.org/10.1158/0008-5472.CAN-21-2161

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