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An engineered SARS-CoV-2 receptor-binding domain produced in Pichia pastoris as a candidate vaccine antigen

Developing affordable and easily manufactured SARS-CoV-2 vaccines will be essential to achieve worldwide vaccine coverage and long-term control of the COVID-19 pandemic. Here the development is reported of a vaccine based on the SARS-CoV-2 receptor-binding domain (RBD), produced in the yeast Pichia...

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Detalles Bibliográficos
Autores principales: Limonta-Fernández, Miladys, Chinea-Santiago, Glay, Martín-Dunn, Alejandro Miguel, Gonzalez-Roche, Diamile, Bequet-Romero, Monica, Marquez-Perera, Gabriel, González-Moya, Isabel, Canaan-Haden-Ayala, Camila, Cabrales-Rico, Ania, Espinosa-Rodríguez, Luis Ariel, Ramos-Gómez, Yassel, Andujar-Martínez, Ivan, González-López, Luis Javier, de la Iglesia, Mariela Perez, Zamora-Sanchez, Jesus, Cruz-Sui, Otto, Lemos-Pérez, Gilda, Cabrera-Herrera, Gleysin, Valdes-Hernández, Jorge, Martinez-Diaz, Eduardo, Pimentel-Vazquez, Eulogio, Ayala-Avila, Marta, Guillén-Nieto, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359770/
https://www.ncbi.nlm.nih.gov/pubmed/35953030
http://dx.doi.org/10.1016/j.nbt.2022.08.002