Pathogenic bacteria remodel central metabolic enzyme to build a cyclopropanol warhead

Bacteria of the Burkholderia pseudomallei (BP) group pose a global health threat, causing the infectious diseases melioidosis, a common cause of pneumonia and sepsis, and glanders, a contagious zoonosis. A trait of BP bacteria is a conserved gene cluster coding for the biosynthesis of polyketides (m...

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Detalles Bibliográficos
Autores principales: Trottmann, Felix, Ishida, Keishi, Ishida-Ito, Mie, Kries, Hajo, Groll, Michael, Hertweck, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359912/
https://www.ncbi.nlm.nih.gov/pubmed/35906404
http://dx.doi.org/10.1038/s41557-022-01005-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359912/
https://www.ncbi.nlm.nih.gov/pubmed/35906404
http://dx.doi.org/10.1038/s41557-022-01005-z

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