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Synaptosome microRNAs regulate synapse functions in Alzheimer’s disease

MicroRNAs (miRNAs) are found in nerve terminals, synaptic vesicles, and synaptosomes, but it is unclear whether synaptic and cytosolic miRNA populations differ in Alzheimer’s disease (AD) or if synaptosomal miRNAs affect AD synapse activity. To address these questions, we generated synaptosomes and...

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Detalles Bibliográficos
Autores principales: Kumar, Subodh, Orlov, Erika, Gowda, Prashanth, Bose, Chhanda, Swerdlow, Russell H., Lahiri, Debomoy K., Reddy, P. Hemachandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359989/
https://www.ncbi.nlm.nih.gov/pubmed/35941185
http://dx.doi.org/10.1038/s41525-022-00319-8