Cargando…

Fragment size and dynamics of EGFR-mutated tumor-derived DNA provide prognostic information regarding EGFR-TKI efficacy in patients with EGFR-mutated NSCLC

Circulating tumor DNA (ctDNA)-based next-generation sequencing (NGS) is a complementary and alternative test to tissue-based NGS. We performed NGS analysis of ctDNA samples collected from patients with EGFR-mutated non-small cell lung cancer (NSCLC) who received osimertinib; the samples were collect...

Descripción completa

Detalles Bibliográficos
Autores principales: Kunimasa, Kei, Nishino, Kazumi, Sato, Yoshiharu, Mori, Masahide, Ihara, Shoichi, Suzuki, Hidekazu, Nagatomo, Izumi, Kumagai, Toru, Morishima, Toshitaka, Imamura, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360008/
https://www.ncbi.nlm.nih.gov/pubmed/35941190
http://dx.doi.org/10.1038/s41598-022-17848-y