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IFN-γ stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii

Dogma holds that Toxoplasma gondii persists in neurons because neurons cannot clear intracellular parasites, even with IFN-γ stimulation. As several recent studies questioned this idea, here we use primary murine neuronal cultures from wild type and transgenic mice in combination with IFN-γ stimulat...

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Detalles Bibliográficos
Autores principales: Chandrasekaran, Sambamurthy, Kochanowsky, Joshua A., Merritt, Emily F., Lagas, Joseph S., Swannigan, Ayesha, Koshy, Anita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360015/
https://www.ncbi.nlm.nih.gov/pubmed/35941154
http://dx.doi.org/10.1038/s41467-022-32225-z