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Proteomic characterization of the Toxoplasma gondii cytokinesis machinery portrays an expanded hierarchy of its assembly and function

The basal complex (BC) is essential for T. gondii cell division but mechanistic details are lacking. Here we report a reciprocal proximity based biotinylation approach to map the BC’s proteome. We interrogate the resulting map for spatiotemporal dynamics and function by disrupting the expression of...

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Detalles Bibliográficos
Autores principales: Engelberg, Klemens, Bechtel, Tyler, Michaud, Cynthia, Weerapana, Eranthie, Gubbels, Marc-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360017/
https://www.ncbi.nlm.nih.gov/pubmed/35941170
http://dx.doi.org/10.1038/s41467-022-32151-0