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Proteomic characterization of the Toxoplasma gondii cytokinesis machinery portrays an expanded hierarchy of its assembly and function
The basal complex (BC) is essential for T. gondii cell division but mechanistic details are lacking. Here we report a reciprocal proximity based biotinylation approach to map the BC’s proteome. We interrogate the resulting map for spatiotemporal dynamics and function by disrupting the expression of...
Autores principales: | Engelberg, Klemens, Bechtel, Tyler, Michaud, Cynthia, Weerapana, Eranthie, Gubbels, Marc-Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360017/ https://www.ncbi.nlm.nih.gov/pubmed/35941170 http://dx.doi.org/10.1038/s41467-022-32151-0 |
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