Methylation of HBP1 by PRMT1 promotes tumor progression by regulating actin cytoskeleton remodeling

HBP1 is a sequence-specific transcription factor which generally considered as a crucial growth inhibitor. Posttranslational modification of HBP1 is vital for its function. In this study, we demonstrate that HBP1 is methylated at R378 by PRMT1, which decreases HBP1 protein stability by promoting its...

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Detalles Bibliográficos
Autores principales: Wang, Jiyin, Yang, Ruixiang, Cheng, Yuning, Zhou, Yue, Zhang, Tongjia, Wang, Shujie, Li, Hui, Jiang, Wei, Zhang, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360041/
https://www.ncbi.nlm.nih.gov/pubmed/35941115
http://dx.doi.org/10.1038/s41389-022-00421-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360041/
https://www.ncbi.nlm.nih.gov/pubmed/35941115
http://dx.doi.org/10.1038/s41389-022-00421-7

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