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Methylation of HBP1 by PRMT1 promotes tumor progression by regulating actin cytoskeleton remodeling
HBP1 is a sequence-specific transcription factor which generally considered as a crucial growth inhibitor. Posttranslational modification of HBP1 is vital for its function. In this study, we demonstrate that HBP1 is methylated at R378 by PRMT1, which decreases HBP1 protein stability by promoting its...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360041/ https://www.ncbi.nlm.nih.gov/pubmed/35941115 http://dx.doi.org/10.1038/s41389-022-00421-7 |