A deletion containing a CTCF-element in intron 8 of the Bbs7 gene is partially responsible for juvenile obesity in the Berlin Fat Mouse

The Berlin Fat Mouse Inbred (BFMI) line is a model for juvenile obesity. Previous studies on crosses between BFMI and C57Bl/6N (B6N) have identified a recessive defect causing juvenile obesity on chromosome 3 (jObes1). Bbs7 was identified as the most likely candidate gene for the observed effect. Co...

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Detalles Bibliográficos
Autores principales: Krause, Florian, Mohebian, Kourosh, Delpero, Manuel, Hesse, Deike, Kühn, Ralf, Arends, Danny, Brockmann, Gudrun A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360062/
https://www.ncbi.nlm.nih.gov/pubmed/34910225
http://dx.doi.org/10.1007/s00335-021-09938-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360062/
https://www.ncbi.nlm.nih.gov/pubmed/34910225
http://dx.doi.org/10.1007/s00335-021-09938-5

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