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What makes a good prediction? Feature importance and beginning to open the black box of machine learning in genetics

Genetic data have become increasingly complex within the past decade, leading researchers to pursue increasingly complex questions, such as those involving epistatic interactions and protein prediction. Traditional methods are ill-suited to answer these questions, but machine learning (ML) technique...

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Detalles Bibliográficos
Autores principales: Musolf, Anthony M., Holzinger, Emily R., Malley, James D., Bailey-Wilson, Joan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360120/
https://www.ncbi.nlm.nih.gov/pubmed/34862561
http://dx.doi.org/10.1007/s00439-021-02402-z