Progranulin mutations in clinical and neuropathological Alzheimer's disease

INTRODUCTION: Progranulin (GRN) mutations occur in frontotemporal lobar degeneration (FTLD) and in Alzheimer's disease (AD), often with TDP‐43 pathology. METHODS: We determined the frequency of rs5848 and rare, pathogenic GRN mutations in two autopsy and one family cohort. We compared Braak sta...

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Detalles Bibliográficos
Autores principales: Vardarajan, Badri N., Reyes‐Dumeyer, Dolly, Piriz, Angel L., Lantigua, Rafael A., Medrano, Martin, Rivera, Diones, Jiménez‐Velázquez, Ivonne Z., Martin, Eden, Pericak‐Vance, Margaret A., Bush, William, Farrer, Lindsay, Haines, Jonathan L., Wang, Li‐San, Leung, Yuk Yee, Schellenberg, Gerard, Kukull, Walter, De Jager, Philip, Bennett, David A., Schneider, Julie A., Mayeux, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360185/
https://www.ncbi.nlm.nih.gov/pubmed/35258170
http://dx.doi.org/10.1002/alz.12567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360185/
https://www.ncbi.nlm.nih.gov/pubmed/35258170
http://dx.doi.org/10.1002/alz.12567

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