A single-cell based precision medicine approach using glioblastoma patient-specific models

Glioblastoma (GBM) is a heterogeneous tumor made up of cell states that evolve over time. Here, we modeled tumor evolutionary trajectories during standard-of-care treatment using multi-omic single-cell analysis of a primary tumor sample, corresponding mouse xenografts subjected to standard of care t...

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Detalles Bibliográficos
Autores principales: Park, James H., Feroze, Abdullah H., Emerson, Samuel N., Mihalas, Anca B., Keene, C. Dirk, Cimino, Patrick J., de Lomana, Adrian Lopez Garcia, Kannan, Kavya, Wu, Wei-Ju, Turkarslan, Serdar, Baliga, Nitin S., Patel, Anoop P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360428/
https://www.ncbi.nlm.nih.gov/pubmed/35941215
http://dx.doi.org/10.1038/s41698-022-00294-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360428/
https://www.ncbi.nlm.nih.gov/pubmed/35941215
http://dx.doi.org/10.1038/s41698-022-00294-4

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