Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner

Metastatic malignant melanoma is the deadliest skin cancer, and it is characterised by its high resistance to apoptosis. The main melanoma driving mutations are part of ERK pathway, with BRAF mutations being the most frequent ones, followed by NRAS, NF1 and MEK mutations. Increasing evidence shows t...

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Detalles Bibliográficos
Autores principales: García-Gutiérrez, Lucía, Fallahi, Emma, Aboud, Nourhan, Quinn, Niall, Matallanas, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360443/
https://www.ncbi.nlm.nih.gov/pubmed/35941108
http://dx.doi.org/10.1038/s41419-022-05147-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360443/
https://www.ncbi.nlm.nih.gov/pubmed/35941108
http://dx.doi.org/10.1038/s41419-022-05147-3

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