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Genetic Analysis of Lung Cancer and the Germline Impact on Somatic Mutation Burden

BACKGROUND: Germline genetic variation contributes to lung cancer (LC) susceptibility. Previous genome-wide association studies (GWAS) have implicated susceptibility loci involved in smoking behaviors and DNA repair genes, but further work is required to identify susceptibility variants. METHODS: To...

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Detalles Bibliográficos
Autores principales: Gabriel, Aurélie A G, Atkins, Joshua R, Penha, Ricardo C C, Smith-Byrne, Karl, Gaborieau, Valerie, Voegele, Catherine, Abedi-Ardekani, Behnoush, Milojevic, Maja, Olaso, Robert, Meyer, Vincent, Boland, Anne, Deleuze, Jean François, Zaridze, David, Mukeriya, Anush, Swiatkowska, Beata, Janout, Vladimir, Schejbalová, Miriam, Mates, Dana, Stojšić, Jelena, Ognjanovic, Miodrag, Witte, John S, Rashkin, Sara R, Kachuri, Linda, Hung, Rayjean J, Kar, Siddhartha, Brennan, Paul, Sertier, Anne-Sophie, Ferrari, Anthony, Viari, Alain, Johansson, Mattias, Amos, Christopher I, Foll, Matthieu, McKay, James D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360465/
https://www.ncbi.nlm.nih.gov/pubmed/35511172
http://dx.doi.org/10.1093/jnci/djac087