Terazosin Analogs Targeting Pgk1 as Neuroprotective Agents: Design, Synthesis, and Evaluation

Nitrogen-containing heterocyclic compounds have shown promising therapeutic effects in a variety of inflammatory and neurodegenerative diseases. Recently, terazosin (TZ), a heterocyclic compound with a quinazoline core, was found to combine with phosphoglycerol kinase 1 (Pgk1) and protect neurons by...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Qian, Shihu, Zhao, Fang, Wang, Yujie, Li, Jiaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360532/
https://www.ncbi.nlm.nih.gov/pubmed/35958233
http://dx.doi.org/10.3389/fchem.2022.906974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360532/
https://www.ncbi.nlm.nih.gov/pubmed/35958233
http://dx.doi.org/10.3389/fchem.2022.906974

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