Cargando…

TGFβ limits Myc-dependent TCR-induced metabolic reprogramming in CD8(+) T cells

T cell activation is dependent upon the integration of antigenic, co-stimulatory and cytokine-derived signals and the availability and acquisition of nutrients from the environment. Furthermore, T cell activation is accompanied by reprogramming of cellular metabolism to provide the energy and buildi...

Descripción completa

Detalles Bibliográficos
Autores principales: Hope, Helen Carrasco, Pickersgill, Gabriella, Ginefra, Pierpaolo, Vannini, Nicola, Cook, Graham P., Salmond, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360539/
https://www.ncbi.nlm.nih.gov/pubmed/35958566
http://dx.doi.org/10.3389/fimmu.2022.913184