Cargando…
TGFβ limits Myc-dependent TCR-induced metabolic reprogramming in CD8(+) T cells
T cell activation is dependent upon the integration of antigenic, co-stimulatory and cytokine-derived signals and the availability and acquisition of nutrients from the environment. Furthermore, T cell activation is accompanied by reprogramming of cellular metabolism to provide the energy and buildi...
Autores principales: | Hope, Helen Carrasco, Pickersgill, Gabriella, Ginefra, Pierpaolo, Vannini, Nicola, Cook, Graham P., Salmond, Robert J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360539/ https://www.ncbi.nlm.nih.gov/pubmed/35958566 http://dx.doi.org/10.3389/fimmu.2022.913184 |
Ejemplares similares
-
Ionic Regulation of T-Cell Function and Anti-Tumour Immunity
por: Ginefra, Pierpaolo, et al.
Publicado: (2021) -
Innate Immune Cells and Their Contribution to T-Cell-Based Immunotherapy
por: Ginefra, Pierpaolo, et al.
Publicado: (2020) -
Enforcing GLUT3 expression in CD8(+) T cells improves fitness and tumor control by promoting glucose uptake and energy storage
por: Cribioli, Elisabetta, et al.
Publicado: (2022) -
Chronic TCR-MHC (self)-interactions limit the functional potential of TCR affinity-increased CD8 T lymphocytes
por: Duong, Minh Ngoc, et al.
Publicado: (2019) -
Coordination of asparagine uptake and asparagine synthetase expression modulates CD8(+) T cell activation
por: Hope, Helen Carrasco, et al.
Publicado: (2021)