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Improvements of nuclease and nickase gene modification techniques for the treatment of genetic diseases

Advancements in genome editing make possible to exploit the functions of enzymes for efficient DNA modifications with tremendous potential to treat human genetic diseases. Several nuclease genome editing strategies including Meganucleases (MNs), Zinc Finger Nucleases (ZFNs), Transcription Activator-...

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Detalles Bibliográficos
Autores principales: Lu, Yaoyao, Happi Mbakam, Cedric, Song, Bo, Bendavid, Eli, Tremblay, Jacques-P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360573/
https://www.ncbi.nlm.nih.gov/pubmed/35958050
http://dx.doi.org/10.3389/fgeed.2022.892769