An LPAR(5)-antagonist that reduces nociception and increases pruriception

INTRODUCTION: The G-protein coupled receptor LPAR(5) plays a prominent role in LPA-mediated pain and itch signaling. In this study we focus on the LPAR(5)-antagonist compound 3 (cpd3) and its ability to affect pain and itch signaling, both in vitro and in vivo. METHODS: Nociceptive behavior in wild...

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Detalles Bibliográficos
Autores principales: Langedijk, Jacqueline, Araya, Erika Ivanna, Barroso, Amanda Ribeiro, Tolenaars, Dagmar, Nazaré, Marc, Belabed, Hassane, Schoene, Jens, Chichorro, Juliana Geremias, Oude Elferink, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pain Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360597/
https://www.ncbi.nlm.nih.gov/pubmed/35959236
http://dx.doi.org/10.3389/fpain.2022.963174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360597/
https://www.ncbi.nlm.nih.gov/pubmed/35959236
http://dx.doi.org/10.3389/fpain.2022.963174

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