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Discovery of TIGIT inhibitors based on DEL and machine learning

Drug discovery has entered a new period of vigorous development with advanced technologies such as DNA-encoded library (DEL) and artificial intelligence (AI). The previous DEL-AI combination has been successfully applied in the drug discovery of classical kinase and receptor targets mainly based on...

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Detalles Bibliográficos
Autores principales: Xiong, Feng, Yu, Mingao, Xu, Honggui, Zhong, Zhenmin, Li, Zhenwei, Guo, Yuhan, Zhang, Tianyuan, Zeng, Zhixuan, Jin, Feng, He, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360614/
https://www.ncbi.nlm.nih.gov/pubmed/35958238
http://dx.doi.org/10.3389/fchem.2022.982539