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Ednrb ( −/− ) mice with hirschsprung disease are missing Gad2-expressing enteric neurons in the ganglionated small intestine
Hirschsprung disease is most often characterized by aganglionosis limited to the distal colon and rectum, and mice lacking the Endothelin receptor type B (Ednrb) faithfully recapitulate this phenotype. However, despite the presence of enteric ganglia in the small intestine, both human patients and E...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360620/ https://www.ncbi.nlm.nih.gov/pubmed/35959491 http://dx.doi.org/10.3389/fcell.2022.917243 |