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Ednrb ( −/− ) mice with hirschsprung disease are missing Gad2-expressing enteric neurons in the ganglionated small intestine

Hirschsprung disease is most often characterized by aganglionosis limited to the distal colon and rectum, and mice lacking the Endothelin receptor type B (Ednrb) faithfully recapitulate this phenotype. However, despite the presence of enteric ganglia in the small intestine, both human patients and E...

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Detalles Bibliográficos
Autores principales:	Bhave, Sukhada, Guyer, Richard A., Picard, Nicole, Omer, Meredith, Hotta, Ryo, Goldstein, Allan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360620/ https://www.ncbi.nlm.nih.gov/pubmed/35959491 http://dx.doi.org/10.3389/fcell.2022.917243

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