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Nucleic Acid Metabolizing Enzyme Levels Predict Chemotherapy Effects in Advanced and Recurrent Colorectal Cancer

BACKGROUND: Thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) predict the effects of fluoropyrimidine. However, the effects of FOLFOX therapy from the perspective of fluorouracil plus leucovorin (FL) remain underexplored. Hence, the relationship between mFOLFOX6 therapy (mFOLFOX6)...

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Detalles Bibliográficos
Autores principales: Watanabe, Mitsuru, Katsumata, Kenji, Sumi, Tetsuo, Ishizaki, Tetsuo, Enomoto, Masanobu, Shigoka, Masatoshi, Wada, Takahiro, Kuwabara, Hiroshi, Mazaki, Junichi, Kasahara, Kenta, Tago, Tomoya, Udo, Ryutaro, Nagakawa, Yuichi, Kawachi, Shigeyuki, Tsuchida, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360946/
https://www.ncbi.nlm.nih.gov/pubmed/35345374
http://dx.doi.org/10.31557/APJCP.2022.23.3.1005