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Therapeutic validation of an orphan G protein‐coupled receptor: The case of GPR84

Despite the importance of members of the GPCR superfamily as targets of a broad range of effective medicines many GPCRs remain poorly characterised. GPR84 is an example. Expression of GPR84 is strongly up regulated in immune cells in a range of pro‐inflammatory settings and clinical trials to treat...

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Detalles Bibliográficos
Autores principales: Marsango, Sara, Barki, Natasja, Jenkins, Laura, Tobin, Andrew B., Milligan, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361006/
https://www.ncbi.nlm.nih.gov/pubmed/32869860
http://dx.doi.org/10.1111/bph.15248