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Hereditary Breast Cancer in the Brazilian State of Ceará (The CHANCE Cohort): Higher-Than-Expected Prevalence of Recurrent Germline Pathogenic Variants

PURPOSE: There is a significant lack of epidemiological data on hereditary cancer in Northeast Brazil. This is the largest study on the prevalence and mutational spectrum of cancer predisposition genes conducted in this region and the first in the State of Ceará. METHODS: Patients ≥18 years of age t...

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Detalles Bibliográficos
Autores principales: Gifoni, Ana Carolina Leite Vieira Costa, Gifoni, Markus Andret Cavalcante, Wotroba, Camila Martins, Palmero, Edenir Inez, Costa, Eduardo Leite Vieira, dos Santos, Wellington, Achatz, Maria Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361024/
https://www.ncbi.nlm.nih.gov/pubmed/35957908
http://dx.doi.org/10.3389/fonc.2022.932957