Mild pentachlorophenol-mediated uncoupling of mitochondria depletes ATP but does not cause an oxidized redox state or dopaminergic neurodegeneration in Caenorhabditis elegans

AIMS: Mitochondrial dysfunction is implicated in several diseases, including neurological disorders such as Parkinson’s disease. However, there is uncertainty about which of the many mechanisms by which mitochondrial function can be disrupted may lead to neurodegeneration. Pentachlorophenol (PCP) is...

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Detalles Bibliográficos
Autores principales: Markovich, Zachary R., Hartman, Jessica H., Ryde, Ian T., Hershberger, Kathleen A., Joyce, Abigail S., Ferguson, Patrick L., Meyer, Joel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361317/
https://www.ncbi.nlm.nih.gov/pubmed/35957653
http://dx.doi.org/10.1016/j.crtox.2022.100084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361317/
https://www.ncbi.nlm.nih.gov/pubmed/35957653
http://dx.doi.org/10.1016/j.crtox.2022.100084

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