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High-content screening of mitochondrial polarization in neural cells derived from human pluripotent stem cells

We present a high-content screening (HCS) protocol for quantifying mitochondrial activity in live neural cells from human induced pluripotent stem cells (iPSCs). The assessment is based on mitochondrial membrane potential, which is influenced by the efficiency of mitochondrial bioenergetics. We desc...

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Detalles Bibliográficos
Autores principales: Zink, Annika, Haferkamp, Undine, Wittich, Annika, Beller, Mathias, Pless, Ole, Prigione, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361325/
https://www.ncbi.nlm.nih.gov/pubmed/35959496
http://dx.doi.org/10.1016/j.xpro.2022.101602