Controlling the Site Selectivity in Acylations of Amphiphilic Diols: Directing the Reaction toward the Apolar Domain in a Model Diol and the Midecamycin A(1) Macrolide Antibiotic

[Image: see text] Seeking to improve the site selectivity of acylation of amphiphilic diols, which is induced by imidazole-based nucleophilic catalysts and directs the reaction toward apolar sites, as we recently reported, we examined a new improved catalytic design and an alteration of the acylatin...

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Detalles Bibliográficos
Autores principales: Fallek, Reut, Ashush, Natali, Fallek, Amit, Fleischer, Or, Portnoy, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361358/
https://www.ncbi.nlm.nih.gov/pubmed/35801540
http://dx.doi.org/10.1021/acs.joc.2c00745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361358/
https://www.ncbi.nlm.nih.gov/pubmed/35801540
http://dx.doi.org/10.1021/acs.joc.2c00745

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