Balanced mitochondrial and cytosolic translatomes underlie the biogenesis of human respiratory complexes

BACKGROUND: Oxidative phosphorylation (OXPHOS) complexes consist of nuclear and mitochondrial DNA-encoded subunits. Their biogenesis requires cross-compartment gene regulation to mitigate the accumulation of disproportionate subunits. To determine how human cells coordinate mitochondrial and nuclear...

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Detalles Bibliográficos
Autores principales: Soto, Iliana, Couvillion, Mary, Hansen, Katja G., McShane, Erik, Moran, J. Conor, Barrientos, Antoni, Churchman, L. Stirling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361522/
https://www.ncbi.nlm.nih.gov/pubmed/35945592
http://dx.doi.org/10.1186/s13059-022-02732-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361522/
https://www.ncbi.nlm.nih.gov/pubmed/35945592
http://dx.doi.org/10.1186/s13059-022-02732-9

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