SESN2 prevents the slow-to-fast myofiber shift in denervated atrophy via AMPK/PGC-1α pathway

BACKGROUND: Sestrin2 (SESN2), a stress-inducible protein, has been reported to protect against denervated muscle atrophy through unfolded protein response and mitophagy, while its role in myofiber type transition remains unknown. METHODS: A mouse sciatic nerve transection model was created to evalua...

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Detalles Bibliográficos
Autores principales: Yang, Xiaofan, Xue, Pingping, Liu, Zhenyu, Li, Wenqing, Li, Chuyan, Chen, Zhenbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361691/
https://www.ncbi.nlm.nih.gov/pubmed/35945510
http://dx.doi.org/10.1186/s11658-022-00367-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361691/
https://www.ncbi.nlm.nih.gov/pubmed/35945510
http://dx.doi.org/10.1186/s11658-022-00367-z

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