N6-methyladenosine-mediated CELF2 regulates CD44 alternative splicing affecting tumorigenesis via ERAD pathway in pancreatic cancer

BACKGROUND: Alternative splicing (AS) of genes has been found to affect gene stability, and its abnormal regulation can lead to tumorigenesis. CELF2 is a vital splicing factor to participate in mRNA alternative splicing. Its downregulation has been confirmed to promote the occurrence and development...

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Detalles Bibliográficos
Autores principales: Lai, Shihui, Wang, Yan, Li, Ting, Dong, Yihong, Lin, Yihao, Wang, Liang, Weng, Shangeng, Zhang, Xiang, Lin, Chengjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361702/
https://www.ncbi.nlm.nih.gov/pubmed/35941702
http://dx.doi.org/10.1186/s13578-022-00844-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361702/
https://www.ncbi.nlm.nih.gov/pubmed/35941702
http://dx.doi.org/10.1186/s13578-022-00844-0

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