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The promising immune checkpoint LAG-3 in cancer immunotherapy: from basic research to clinical application
LAG-3, a type of immune checkpoint receptor protein belonging to the immunoglobulin superfamily, is confirmed to be expressed on activated immune cells, mainly including activated T cells. LAG-3 can negatively regulate the function of T cells, exerting important effects on maintaining the homeostasi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361790/ https://www.ncbi.nlm.nih.gov/pubmed/35958563 http://dx.doi.org/10.3389/fimmu.2022.956090 |