The promising immune checkpoint LAG-3 in cancer immunotherapy: from basic research to clinical application

LAG-3, a type of immune checkpoint receptor protein belonging to the immunoglobulin superfamily, is confirmed to be expressed on activated immune cells, mainly including activated T cells. LAG-3 can negatively regulate the function of T cells, exerting important effects on maintaining the homeostasi...

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Detalles Bibliográficos
Autores principales: Huo, Jin-Ling, Wang, Ya-Tao, Fu, Wen-Jia, Lu, Nan, Liu, Zhang-Suo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361790/
https://www.ncbi.nlm.nih.gov/pubmed/35958563
http://dx.doi.org/10.3389/fimmu.2022.956090

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