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“Calcium bombs” as harbingers of synaptic pathology and their mitigation by magnesium at murine neuromuscular junctions

Excitotoxicity is thought to be an important factor in the onset and progression of amyotrophic lateral sclerosis (ALS). Evidence from human and animal studies also indicates that early signs of ALS include degeneration of motor nerve terminals at neuromuscular junctions (NMJs), before degeneration...

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Detalles Bibliográficos
Autores principales: Dissanayake, Kosala N., Redman, Robert R., Mackenzie, Harry, Eddleston, Michael, Ribchester, Richard R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361872/
https://www.ncbi.nlm.nih.gov/pubmed/35959105
http://dx.doi.org/10.3389/fnmol.2022.937974